Research Services

Tihondan is mainly engaged in the foreign trade business of pharmaceutical intermediates in the early stage, and has established long-term and stable cooperative relations with domestic and foreign customers. After early accumulation, we now plan to cooperate with taiyuan university of technology to carry out the whole chain business of CRO (pharmaceutical contract r&d enterprise), CMO (customized pharmaceutical contract production) and CDMO (customized pharmaceutical contract r&d and production), which can provide domestic and foreign pharmaceutical companies with the following three types of services :(1) research and development contract research services for new drugs and their intermediates; (2) Mass customization production services for pharmaceutical products; (3) Customized research, development and production services for pharmaceutical products, such as process development and preparation, process optimization, amplification and commercial production.

Research services include:

Discovery Process Chemistry

Bridge discovery chemistry and process chemistry by providing FFS services in

rapid scale up and process research and development

Synthesis of non-GMP key intermediates and reference compounds

Synthesis of non-GMP drug substances for e-IND toxicity studies with early stage

process development

Strong capability in new route scouting and process optimization, shorten the

cycle time of API research

Isolation, characterization, synthesis and control of the impurities in process

chemistry research and development

Library Design & Synthesis

18 Years of experience in high-quality services on combinatorial chemistry and

small molecule library design and synthesis, with more than 3 million compounds

delivered so far, providing fast and comprehensive research support in drug

discovery and agro / crop science projects worldwide

Offering world class service in design and synthesis of all library types at

competitive price, such as parallel medicinal chemistry library, library

enrichment project, focused / targeted library and virtual library

Streamlined process with high efficiency to accelerate library production. As

quick as 7 calendar days from project initiation to whole library delivery

Exceeding client’s expectation on product quality by strict and multi-level

quality control procedures. Each compound is checked by LCMS and/or 1H NMR

before delivery

Heavy investment to build up in house reaction condition screening platform to

speed up problem solving and increase success rate

Applying cutting-edge chemistry methodologies such as photoredox chemistry to

library synthesis. Finalized several photoredox libraries with up to 100%

success rate

Over 25,000 reagents and 8,000 unique scaffolds / building blocks in stock to

facilitate library design with novelty and diversity, and expedite library

production with material readiness for bench chemists within 24 hours.

If you have any questions or requests, please contact us through the following ways: sales@tihondan.com